Rotation Projects
The Mayer-Pröschel Laboratory seeks highly motivated individuals who have an interest in the fields of Iron Deficiency, Virus infection in Multiple Sclerosis, Glial Cell contribution to Degenerative Disease, or general percursor biology. We have a weekly laboratory meeting which includes the Noble and Pröschel laboratories as well as a weekly Glial Journal Club. Rotation students typically work side-by-side with senior students or Postdoctoral Fellows and are required to give one laboratory meeting presentation at the conclusion of their rotation project and strongly encouraged to present an article at the weekly Glial Journal Club.
Iron Deficiency
1.Iron restriction effects on cochlear nerve myelination.
2. Astrocyte Dysfunction due to Gestational Iron Deficiency
3. Molecular explanations for the consequences of gestation iron deficiency on postnatal glial processes
General Cell Biology
1. GDA1 versus GDA2 astrocyte generation from tGRPs and their roles in spinal cord injury repair.
2. Disruption of Neural Stem Cell Differentiation due to Toxicant Exposure (Collaboration with Dr. Lisa Opanashuk)
3. The role of the tGRP in forebrain development and the implications for gray and white matter formation.
4. Optimization of hybridoma cell antibody production, purification and fluorophore conjugation.
5. Development of a genotyping assay for transgenic rats using Fluorescence In Situ Hybridization (FISH).
Human Herpes Virus-6 Related
1. Investigation into the Mechanism of HHV-6 induced Glial Precursor Cell Cycle Arrest
2. Astrocyte dysfunction due to HHV-6 infection